Can prenatal ultrasound predict adverse neonatal outcomes in SARS-CoV-2-affected pregnancies?
American Journal of Obstetrics & Gynecology MFM · 2023
After COVID-19 in pregnancy, fetal growth restriction seen on ultrasound was linked to a much higher rate of adverse newborn outcomes.
Research question
Can prenatal ultrasound findings predict adverse neonatal outcomes after SARS-CoV-2 infection in pregnancy?
Clinical & scientific significance
Pregnancies with fetal growth restriction after SARS-CoV-2 infection may warrant close surveillance.
Key findings reported in the paper
- Of 100 included pregnancies, 28 of 97 infants with outcome data (29%) had the composite adverse neonatal outcome; 23% had at least one abnormal ultrasound finding.
- Most common abnormalities: placentomegaly (47.8%) and fetal growth restriction (34.8%).
- Fetal growth restriction was associated with the adverse outcome (adjusted OR 22.67, 95% CI 2.63–194.91); third-trimester infection was associated with lower estimated fetal weight percentile.
Objectives
To describe sonographic findings after confirmed infection and test their association with a composite adverse neonatal outcome.
Methods
Prospective observational cohort (March 2020–May 2021) with at least one ultrasound after diagnosis: biometry, umbilical and middle cerebral artery Doppler, placental thickness, amniotic fluid and anatomic survey.
This summary is based only on the published abstract.
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Authors
Mei JY, Mok T, Cambou MC, Fuller T, Fajardo VM, Kerin T, Han CS, Nielsen-Saines K, Rao R
Citation
Can prenatal ultrasound predict adverse neonatal outcomes in SARS-CoV-2-affected pregnancies?. Am J Obstet Gynecol MFM. 2023; 5(9):101028. doi:10.1016/j.ajogmf.2023.101028. PMID: 37295718.
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